Full Name  Graeme Whyte
Phone  +44 (0)131 451 3053
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Address Room G44
David Brewster Building
Heriot-Watt University
Edinburgh
EH14 4AS
United Kingdom

 

Graeme uses optical forces within microfluidic environments to controllable hold and manipulate living cells. Recent developments have included aimed to overcome the anisotropic nature of microscope resolution limits by accurately rotating cells held within a dual-beam optical trap, allowing the cell to be imaged from multiple directions and thus improved 3D imaging capabilities.

 

GW image 1Schematic of Graeme's work using lasers to manipulate cell rotation

 

Some relevant publications:

  • M Kreysing, D Ott, M Schmidberger,  O Otto, M Schürmann, E Martín-Badosa, G Whyte, J Guck. Dynamic operation of optical fibres beyond single-mode regime facilitates the orientation of biological cells. Nature Communications, 5 5481 (2014)
  • T Kolb, S Albert, M Haug, G Whyte. Optofluidic rotation of living cells for single-cell tomograph., J. Biophotonics, 106 (2014)
  • T Kolb, S Albert, M Haug, G Whyte, Dynamically reconfigurable Optical Spanner. Lab on a Chip, 14, 1186 (2014)