Full Name  Weiping Lu
Phone 0131 451 3065
Email This email address is being protected from spambots. You need JavaScript enabled to view it. 

2.12 David Brewster Building
Heriot-Watt University
EH14 4AS
Heriot-Watt University


Weiping’s research interests are in the areas of nonlinear optical systems and at the interface between physics and biology. He is an established researcher in nonlinear dynamics, nonlinear optics and bio-imaging processing with more than 100 peer reviewed journal papers He received the Makdougall-Brisbane Prize in 1997 from the Royal Society of Edinburgh for his research contribution to nonlinear dynamics and chaos. His recent interests include nonlinear and dynamical systems for image processing and particle tracking in biological applications, where his contributions include the first nonlinear dynamical system for detection and tracking of small moving objects in low SNR images. Over the last 5 years he has developed a range of advanced computational methods for image processing and analysis, including feature detection, segmentation and tracking, and a novel translation microscopy technique for super-resolution restoration. Weiping's specifics areas of expertise include; Nonlinear Optical Systems, Nonlinear Dynamics and Chaos, Image Processing, Particle Tracking, Super-resolution Image Restoration.

TRAM WLMicrotubules (green), Actin (red) and DNA (blue) imaged under confocal microscopy (right) and using Translational Microscopy (TRAM) (right), published in 2016 http://www.nature.com/articles/srep19993

Some relevant publications:

  • Wilson, R. S., Yang, L., Dun, A., Smyth, A. M., Duncan, R. R., Rickman, C. & Lu, W. Automated single particle detection and tracking for large microscopy datasets. May 2016 In : Royal Society Open Science. 3, 5, 160225
  • Qiu, Z., Wilson, R. S., Liu, Y., Dun, A., Saleeb, R. S., Liu, D., Rickman, C., Frame, M., Duncan, R. & Lu, W. Translation Microscopy (TRAM) for super-resolution imaging. 29 Jan 2016 In : Scientific Reports. 6, 19993
  • Kavanagh, D., Smyth, A. M., Martin, K. J., Dun, A., Brown, E. R., Gordon, S., Smillie, K. J., Chamberlain, L. H., Wilson, R. S., Yang, L., Lu, W., Cousin, M. A., Rickman, C. & Duncan, R. R. A molecular toggle after exocytosis sequesters the presynaptic syntaxin1a molecules involved in prior vesicle fusion. 2014 In : Nature Communications. 5, 5774
  • Smyth, A. M., Yang, L., Martin, K. J., Hamilton, C., Lu, W., Cousin, M. A., Rickman, C. & Duncan, R. R. Munc 18-1 Protein Molecules Move between Membrane Molecular Depots Distinct from Vesicle Docking Sites. 15 Feb 2013 : In: Journal of Biological Chemistry. 288, 7, p. 5102-5113 12 p.
  • Yang, L., Qiu, Z., Greenaway, A. H. & Lu, W. A New Framework for Particle Detection in Low-SNR Fluorescence Live-Cell Images and Its Application for Improved Particle Tracking. Jul 2012 In : IEEE Transactions on Biomedical Engineering. 59, 7, p. 2040-50 11 p.

Full list: https://pureapps2.hw.ac.uk/portal/en/persons/weiping-lu(49bf3b9c-3421-4d88-982d-de9f9764ee9e).html