Choosing the best super-resolution technique for your research
Choosing the right super-resolution technique to answer a given biological question is vital for understanding and interpreting biological relevance. Given the wide range of techniques available, and the inevitable trade-offs in imaging capabilities of each, this can be a daunting task.
The simplified guide below can help you to select the best technique for your research, taking into account sample type, structure size, and imaging requirements.
For a more detailed overview of the concepts underlying the most common super-resolution techniques and the aspects that should be considered in selecting the most appropriate technique, please see the JBC review recently published by ESRIC.